Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + miR-21-5p | Homo sapiens | enzyme isoform PAPD5 adenylates the 3'-end of miR-21-5p, marking it for 3'-to-5'-trimming by the poly(A) specific ribonuclease PARN | ? | - |
? | |
ATP + RNAn | Homo sapiens | - |
diphosphate + RNAn+1 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q8NDF8 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast cancer cell | - |
Homo sapiens | - |
BT-474 cell | - |
Homo sapiens | - |
SK-BR-3 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + miR-21-5p | enzyme isoform PAPD5 adenylates the 3'-end of miR-21-5p, marking it for 3'-to-5'-trimming by the poly(A) specific ribonuclease PARN | Homo sapiens | ? | - |
? | |
ATP + RNAn | - |
Homo sapiens | diphosphate + RNAn+1 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 63000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
PapD5 | - |
Homo sapiens |
poly(A) polymerase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | the mature miRNA miR-4728-3p downregulates isoform PAPD5 | down |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in non-templated 3'-adenylation of miRNAs | Homo sapiens |